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Tb Vaccine

All articles tagged with #tb vaccine

health-medicine1 year ago

"Advancements in TB Vaccine Trials: Progress in India and South Africa"

Bharat Biotech has initiated clinical trials of MTBVAC, a potentially more effective TB vaccine derived from a human source, in India. The vaccine, developed in collaboration with Spanish biopharma player Biofabri, aims to provide better protection against tuberculosis for newborns, adolescents, and adults. MTBVAC is designed to be more effective and longer-lasting than the existing BCG vaccine, particularly in preventing pulmonary TB. The clinical trials in India mark a significant step in the global effort to develop improved TB vaccines, with the potential to address the high burden of TB cases in the country.

health2 years ago

"Major Funding Boosts Development of Groundbreaking TB Vaccine"

Wellcome and the Bill & Melinda Gates Foundation are investing around $550 million to fund the final stage of trials for the M72 vaccine, which could be the first new vaccine against tuberculosis (TB) in over a century. TB, a preventable and treatable bacterial disease, still affects 10 million people annually, causing 1.6 million deaths in 2021. The trial, set to take 4-6 years and involve 26,000 people across Africa and Southeast Asia, aims to test the vaccine's efficacy in preventing latent TB from becoming active. The existing TB vaccine, BCG, offers limited protection and wears off over time. The M72 vaccine showed around 50% efficacy in Phase II trials and could potentially save 8.5 million lives over 25 years, according to the World Health Organization.

health2 years ago

Disappointing Results for BCG Vaccine in COVID-19 Prevention

A clinical trial of the century-old TB vaccine, B.C.G., found that it did not prevent Covid infections among health care workers. The trial was shorter and smaller than originally designed, and the results did not rule out other potential benefits associated with the vaccine. The B.C.G. vaccine is still widely used in the developing world, where it reduces infant mortality rates and protects against other diseases. Additional analysis of the data collected from inoculated health care workers is continuing, and the vaccine's effects may vary depending on the virus or bacterium it is pitted against.