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Proteinfolding

All articles tagged with #proteinfolding

technology1 year ago

Lessons from Navigating AI in Biotechnology

Naren Tallapragada, CEO of Tessel Bio, discusses the limitations and potential of AI in biology, emphasizing that while AI models like AlphaFold have advanced protein folding predictions, they cannot yet fully model biological systems such as cells or tissues. He highlights the importance of real data, as seen in successful startups like Fauna Bio and Enveda, which have built extensive databases to support their AI models. Tallapragada advocates for "augmented intelligence," where AI assists in guiding experiments, as a practical approach in drug discovery.

science1 year ago

AI and Chemistry: The Nobel Prize Connection

John Jumper, a Nobel laureate in Chemistry, initially struggled with chemistry but found his passion in computational modeling of protein folding. His work at the University of Chicago and later at DeepMind led to the development of AlphaFold, an AI program that predicts protein structures from genetic sequences. This breakthrough has significant implications for understanding diseases and drug development, earning Jumper and his colleague Demis Hassabis the 2024 Nobel Prize in Chemistry.