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Progression Free Survival

All articles tagged with #progression free survival

Enhancing Ovarian Cancer Survival Rates through Multidisciplinary Surgical Teams

Originally Published 2 years ago — by AJMC.com Managed Markets Network

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Source: AJMC.com Managed Markets Network

A study published in Annals of Surgical Oncology reveals that implementing a multidisciplinary surgical approach significantly improves overall survival (OS) in patients with ovarian cancer. The study, conducted at Mater University Hospital, found that patients who underwent the new approach experienced a 70% improvement in OS compared to previous therapies. The multidisciplinary surgical team (MDT) approach, which involved collaboration among various surgical disciplines, aimed to eliminate all visible tumors within patients' abdomens. The study also identified residual disease and age as independent predictors of survival. The findings highlight the importance of a multidisciplinary approach in achieving optimal treatment outcomes and improved quality of life for ovarian cancer patients.

Merck's WELIREG® Phase 3 Trial Shows Promising Results in Advanced Renal Cell Carcinoma

Originally Published 2 years ago — by Merck

Featured image for Merck's WELIREG® Phase 3 Trial Shows Promising Results in Advanced Renal Cell Carcinoma
Source: Merck

Merck has announced positive Phase 3 trial results for WELIREG (belzutifan), its oral hypoxia-inducible factor-2 alpha (HIF-2α) inhibitor, in the treatment of advanced renal cell carcinoma (RCC) that has progressed following PD-1/L1 checkpoint inhibitor and vascular endothelial growth factor-tyrosine kinase inhibitor (VEGF-TKI) therapies. The trial showed statistically significant improvements in progression-free survival (PFS) compared to everolimus, as well as a significant improvement in objective response rate (ORR). While there was a trend towards improvement in overall survival (OS), it did not reach statistical significance. The safety profile of WELIREG was consistent with previous studies.