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Phosphorus Fluoride Exchange

All articles tagged with #phosphorus fluoride exchange

"Revolutionary New Reaction Unveiled in Click Chemistry Research"
science-and-technology2 years ago

"Revolutionary New Reaction Unveiled in Click Chemistry Research"

Chemists John Moses and Barry Sharpless have developed a new technique called phosphorus fluoride exchange (PFEx) that enables scientists to easily build oxygen and nitrogen-linked products from a central phosphorus hub. The PFEx reaction is done under mild conditions and operates orthogonally to other click reactions, allowing the new technique to function harmoniously alongside established reactions. The researchers hope that greater diversity in clicked molecules will lead to discoveries, including new bioactive molecules.

Biology's Favorite Chemical: A Key Tool for Scientists.
science-and-technology2 years ago

Biology's Favorite Chemical: A Key Tool for Scientists.

Scientists have developed a new technique called phosphorus fluoride exchange (PFEx), which uses phosphorous as a chemical connector to construct complex molecules, expanding the realm of click chemistry. This advancement could potentially contribute to the discovery of effective cancer therapeutics and the creation of new materials with beneficial properties like flame retardance or antimicrobial effects, while maintaining environmental sustainability as phosphorous bonds can be broken down easily during recycling.