All articles tagged with #osteopontin
A new review argues that the bone-brain axis is a real physiological network in which bone-derived signals such as osteocalcin and osteopontin can affect brain function and mood, while depression and stress hormones can contribute to bone loss; recognizing this two-way communication could lead to integrated treatments (including exercise, neuromodulation, or bone-targeted therapies) and more targeted clinical research.
Researchers from the University of California have discovered a molecule called osteopontin that stimulates hair follicle stem cells and promotes hair growth. The molecule, found in higher levels in hairy moles, has the potential to pave the way for future hair loss treatments. Clinical trials are set to begin this summer to evaluate the safety and tolerability of osteopontin as a potential solution for hair loss.
Scientists have discovered that molecules found in mole hair, specifically osteopontin, may hold the key to developing a new Botox-like treatment for baldness. In mouse models, injecting osteopontin into the scalp reactivated dormant hair follicles and stimulated new hair growth. However, further research is needed to determine if this treatment will be effective on human hair. The potential treatment offers a promising solution for age-related hair loss, which currently only has limited treatment options available. Human trials for this new hair treatment are set to begin in the coming weeks.
A study published in the journal Nature suggests that skin moles that grow hair may offer a possible avenue to treat hair loss. Scientists at the University of California, Irvine have been studying skin moles to understand why they produce such long hairs. Their new paper shows that such moles contain particular molecules that promote hair growth. In experiments involving mice, a molecule called osteopontin, which is especially prominent in hairy skin moles, could activate hair follicle stem cells that were previously dormant. The researchers hope that their research could eventually lead to an outpatient procedure to promote hair growth.
Scientists have discovered that senescent pigment cells in skin moles can stimulate robust hair growth, challenging the belief that these cells impede regeneration. The study showed that molecules osteopontin and CD44 play a key role in this process, potentially opening new avenues for therapies for common hair loss conditions. The growth of hair follicles is well regulated by stem cell activation; these cells divide, enabling follicles to produce new hair in a cyclical manner. Androgenetic alopecia, also known as male or female pattern baldness, is the most common type of hair loss affecting both men and women.