Tag

Organic Synthesis

All articles tagged with #organic synthesis

chemistry2 years ago

Revolutionizing Cross-Coupling: Geminal-Atom Catalysis Unleashed

Researchers have developed geminal-atom catalysis, a new approach for cross-coupling reactions in organic synthesis. This method bridges the gap between homogeneous and heterogeneous catalysis by utilizing heterogeneous single-metal-site catalysts. Geminal-atom catalysis offers potential advantages such as improved selectivity, recyclability, and scalability, making it a promising tool for sustainable organic synthesis. The data for this study are available in the manuscript and supplementary information, as well as in the Zenodo repository.

chemistry2 years ago

Isomer of Benzene gains prominence in organic synthesis.

Researchers have demonstrated that the high energy compound 1,2,3-cyclohexatriene, an overlooked isomer of benzene, can participate in a diverse range of cycloaddition, nucleophilic addition, and σ-bond insertion reactions, enabling chemists to construct complex molecular architectures in just a few steps. The team hopes that its work inspires others to explore and exploit the synthetic potential of these high-energy reagents going forwards.