Revolutionizing Cross-Coupling: Geminal-Atom Catalysis Unleashed

Researchers have developed geminal-atom catalysis, a new approach for cross-coupling reactions in organic synthesis. This method bridges the gap between homogeneous and heterogeneous catalysis by utilizing heterogeneous single-metal-site catalysts. Geminal-atom catalysis offers potential advantages such as improved selectivity, recyclability, and scalability, making it a promising tool for sustainable organic synthesis. The data for this study are available in the manuscript and supplementary information, as well as in the Zenodo repository.