Tag

Orelabrutinib

All articles tagged with #orelabrutinib

multiple-sclerosis2 years ago

New Developments in MS Treatment and Lifestyle Factors.

Orelabrutinib, a Bruton’s tyrosine kinase inhibitor, has shown promising results in reducing brain lesions in a Phase 2 trial for relapsing-remitting multiple sclerosis. A Phase 2 clinical trial for foralumab, an antibody-based nasal spray, is set to launch later this year for people with nonactive secondary progressive MS. Research suggests that adhering to high-quality diets such as McDougall, paleo, Swank, and Overcoming MS may help ease depression in MS patients. A small study in Iran suggests that drinking coffee and tea may protect against MS, but the self-reporting survey used in the study has limitations.

health2 years ago

Orelabrutinib shows promising results in reducing RRMS brain lesions.

InnoCare Pharma's orelabrutinib, an experimental inhibitor of the Bruton's tyrosine kinase (BTK) enzyme, has shown significant reductions in new active brain lesions among people with relapsing-remitting multiple sclerosis (RRMS) in a 12-week interim analysis of a global Phase 2 trial. The trial has met its main goal, overall "supporting further development" of orelabrutinib for MS. Orelabrutinib is expected to ease inflammation and slow MS progression by preventing the activation of immune cell populations implicated in MS, namely B-cells and macrophages.