"Unveiling the Link Between Iron Buildup and Cell Death in Alzheimer's"
Researchers have discovered a new form of cell death called ferroptosis, triggered by iron accumulation, which destroys microglia cells in Alzheimer's disease and vascular dementia. The study found that microglia degenerates in the white matter of the brain while attempting to clear iron-rich myelin. This new insight into the role of microglial degeneration in neurodegenerative diseases could lead to the development of novel therapeutic interventions.