Tag

Lipidomics

All articles tagged with #lipidomics

scientific-research1 year ago

"Cholesterol Precursor 7-Dehydrocholesterol Suppresses Ferroptosis Sensitivity in Cells"

A study has found that 7-dehydrocholesterol, a precursor to cholesterol, plays a crucial role in determining the sensitivity of cells to ferroptosis, a form of cell death. The research, which utilized CRISPR screening and lipidomic analysis, provides insights into the mechanisms underlying ferroptosis and its potential implications for various diseases. The data from the study are available online, contributing to the accessibility and reproducibility of the findings.

scientific-research1 year ago

"Cholesterol Precursor 7-Dehydrocholesterol Suppresses Ferroptosis in Cells"

A study has identified 7-dehydrocholesterol as a natural inhibitor of ferroptosis, a form of cell death driven by lipid peroxidation. The research sheds light on the role of 7-dehydrocholesterol-derived oxysterols in regulating ferroptosis sensitivity and provides insights into the mechanisms of this type of cell death. The data and materials supporting the findings are available in the main text, figures, and extended data figures, as well as in a repository for (epi)lipidomics experiments.