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Limbal Stem Cell Deficiency

All articles tagged with #limbal stem cell deficiency

health1 year ago

Breakthrough Stem Cell Therapy Restores Vision in Corneal Patients

A groundbreaking clinical trial in Japan has successfully used induced pluripotent stem cells (iPSCs) to restore vision in patients with limbal stem cell deficiency (LSCD), a condition causing corneal damage. The trial involved transplanting iPSC-derived corneal epithelial cell sheets onto the corneas of four patients, resulting in significant vision improvements for three of them. This marks a world-first achievement in stem cell research, offering hope for new treatments for corneal vision loss, though further research is needed to ensure safety and efficacy.

health1 year ago

Stem Cell Breakthrough Restores Vision in Medical First

Researchers at Osaka University have successfully conducted the first human trial using induced pluripotent stem-cell-derived corneal epithelium to treat limbal stem cell deficiency, a condition causing vision impairment. The study involved transplanting iPSC-derived corneal epithelial sheets onto affected eyes of four patients, resulting in significant vision improvements and enhanced quality of life. This breakthrough offers a promising alternative to traditional treatments, reducing the need for immunosuppression and HLA matching, and marks a significant advancement in regenerative medicine.

health1 year ago

Japan's Stem Cell Breakthrough Restores Vision for Blind Patients

A groundbreaking stem cell treatment has restored vision in three out of four participants by repairing damaged corneas affected by limbal stem-cell deficiency (LSCD). The treatment, developed by Osaka University researchers, uses induced pluripotent stem cells to create corneal epithelial cell sheets for transplantation. Despite one participant experiencing a reversal, the results are promising, with no severe side effects observed over two years. Clinical trials are planned to further assess the treatment's efficacy.