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Laboratory Applications

All articles tagged with #laboratory applications

science-and-technology2 years ago

Unraveling DNA's Hidden Potential: The Intricate Folding Revealed

Researchers have discovered that DNA can mimic the functions of proteins by forming intricate, three-dimensional structures. Using high-definition imaging technologies, scientists uncovered the unique configuration of a synthesized DNA molecule that emulates the behavior of green fluorescent protein (GFP). This breakthrough in understanding DNA folding opens up possibilities for creating DNA molecules with complex shapes for various laboratory and clinical applications, such as fluorescent tags for diagnostic tests. The findings advance the field of DNA-based tools and highlight the potential of DNA beyond its role as a genetic information store.

science2 years ago

DNA's complex folding enables new functions.

Researchers at Weill Cornell Medicine and the National Heart, Lung, and Blood Institute have discovered that DNA can fold into complex, three-dimensional structures that mimic protein functions. The team used high-resolution imaging techniques to reveal the structure of a DNA molecule that mimics the activity of green fluorescent protein (GFP), which is often used as a fluorescent tag in cells. The findings will help researchers build DNA molecules for a variety of laboratory and clinical applications, including inexpensive fluorescent tags for labeling targeted pieces of DNA in biological studies and diagnostic test kits.