Revolutionary Therapy Boosts Immune System to Combat Brain Tumors with Nanotechnology
Researchers from Uppsala University have developed a new therapy that uses a viral vector to help killer T cells reach brain tumors and fight cancer cells. The viral vector induces production of LIGHT in the blood vessels, which tailors their function to recruit killer T cells into the tumor. The therapy also induced the formation of immune cell aggregates known as tertiary lymphoid structures (TLS) in association with the brain tumor, which increased the sensitivity to cancer immunotherapy. The researchers hope to further develop this therapy to determine if it can be used for patients with glioblastoma.
