Tag

Human Genetics

All articles tagged with #human genetics

health-and-genomics1 year ago

"Uncovering New Genetic Variants: Advancements in Precision Medicine and Genetic Risk Prediction"

The All of Us Research Program has released genomic data from 245,388 participants, with 77% from under-represented communities. The dataset includes over 1 billion genetic variants, with 275 million previously unreported variants. The program aims to accelerate health research by providing summary data publicly and individual-level data to researchers through a secure cloud-based platform. The data has been validated for genetic associations and is available for diverse research projects, with a streamlined access model reducing barriers for authorized researchers.

science2 years ago

The Hidden Powers of Sex Chromosomes Revealed by Study

A new study reveals that sex chromosomes, specifically the X and Y chromosomes, have a broader impact on gene regulation throughout the body than previously thought. Genes expressed from the X and Y chromosomes influence cells beyond the reproductive system by affecting the expression of thousands of genes found on other chromosomes. The gene pair ZFX and ZFY, found on the X and Y chromosomes respectively, play a significant role in this regulatory behavior. These findings suggest that sex chromosomes contribute widely to functions beyond those related to sex characteristics and may help explain the differences between male and female cells. The study also challenges the traditional understanding of sex chromosomes, highlighting the importance of the inactive X chromosome and the Y chromosome in gene regulation.