"Link Found Between Fat Build-Up in Brain Cells and Alzheimer's Risk"
A new study suggests that fat droplets within brain cells may be a key factor in causing Alzheimer's disease, potentially opening up a new avenue for therapeutic development. Researchers found that the APOE4 gene variant, a major risk factor for Alzheimer's, is associated with increased fat storage in immune brain cells, which could lead to tau tangles in neurons and subsequent memory loss. This finding challenges the long-held belief that protein culprits are solely responsible for the disease and highlights the potential impact of targeting fat metabolism in developing more effective treatments.