Tag

Enzymediscovery

All articles tagged with #enzymediscovery

science-and-health2 years ago•1 min saved

"Researchers Uncover Enzyme Behind the Yellow Color of Urine"

Scientists have discovered the enzyme bilirubin reductase, produced by gut microbes, which is responsible for converting bilirubin into urobilinogen and ultimately causing the yellow color in urine. This finding solves a mystery that has puzzled researchers for over a century and opens up new avenues for studying gut health and diseases like jaundice and inflammatory bowel disease. The enzyme is present in most healthy adults but absent in newborns and those with inflammatory bowel disease, highlighting its potential importance in human health.

via NDTV|

##bilirubin #enzymediscovery

science2 years ago•3 min saved

"Scientists Uncover the Enzyme Behind Urine's Yellow Hue"

Scientists have discovered the enzyme responsible for the yellow color of urine, solving a long-standing biological mystery. The enzyme, bilirubin reductase, is produced by gut microbes and converts bilirubin into urobilinogen, which then degrades into urobilin, the pigment that gives urine its yellow hue. This finding, published in Nature Microbiology, could have implications for understanding gut health, inflammatory bowel disease, and jaundice. The research also highlights that the presence of different colors in urine can indicate various health conditions or dietary influences.

via CBS News|

##bilirubin #enzymediscovery

science-and-health2 years ago•49 min saved

"Exploring BilR: The Microbial Enzyme Transforming Bilirubin in the Gut"

Researchers have identified a gut microbial enzyme named BilR that converts bilirubin into urobilinogen, a key process in the human body's haem degradation pathway. This discovery fills a significant gap in understanding how gut microbiota influence serum bilirubin levels, which are crucial for maintaining health. Bilirubin acts as an antioxidant at moderate levels but can be toxic when elevated. The presence of the bilirubin reductase gene was found to be nearly universal in healthy adults but less prevalent in patients with inflammatory bowel disease and infants, who are at higher risk for jaundice. This breakthrough provides a foundation for further research into disorders related to serum bilirubin homeostasis.

via Nature.com|

##bilirubinreduction #enzymediscovery