All articles tagged with #dgat2 enzyme
A new study suggests that fat buildup in brain cells, particularly involving the enzyme DGAT2, impairs immune cell function in Alzheimer's disease, offering a potential new target for treatment by restoring microglial activity.
Purdue University researchers have discovered that excess fat in brain immune cells impairs their ability to fight Alzheimer's disease, revealing a new lipid-based mechanism involving the enzyme DGAT2. Targeting this enzyme to reduce fat accumulation in microglia restores their function and offers a promising therapeutic approach for neurodegeneration.