Uncovering the Mechanisms of Circadian Rhythms
Researchers have revealed the structure of cryptochrome-timeless, a protein complex that plays a key role in the circadian clock. The study sheds light on the mechanisms behind the timing of the body's internal clock and could lead to new treatments for sleep disorders. The researchers used a combination of X-ray crystallography and cryo-electron microscopy to determine the structure of the complex, which is found in both humans and fruit flies.