Tag

Crispr Screens

All articles tagged with #crispr screens

cancer-research2 months ago•81 min saved

PTGES3 Identified as Key Regulator of Androgen Receptor in Prostate Cancer

Genome-scale CRISPR screens identified PTGES3 as a key regulator of androgen receptor (AR) stability and activity in advanced prostate cancer, revealing its potential as a therapeutic target to overcome resistance to AR-targeted therapies in castration-resistant prostate cancer (CRPC).

via Nature|

#androgen-receptor #cancer-research #crispr-screens

science3 months ago•27 min saved

LRP8 Protein Key to Tick-Borne Encephalitis Virus Infection

The study identifies LRP8 as a receptor for tick-borne encephalitis virus through genome-wide CRISPR screens and various molecular biology techniques, providing insights into virus entry mechanisms.

via Nature|

#crispr-screens #flavivirus #lrp8