Crucial Protein and Enhancer Module Unveil Neural Development Secrets
Researchers at the Wistar Institute have identified the protein subunit INST10 as crucial for guiding pluripotent stem cells to develop into neural cells, maintaining their identity and preventing them from becoming other cell types. This discovery sheds light on the molecular processes of neurogenesis and links mutations in the Integrator protein complex to neurodevelopmental disorders, offering new insights into early neural development.