Tag

Cefepime

All articles tagged with #cefepime

medical-research2 years ago•26 min saved

Comparing Cefepime and Piperacillin-Tazobactam for Acute Infections in Hospitalized Adults

A randomized clinical trial compared the safety of cefepime and piperacillin-tazobactam, two commonly used antibiotics for treating acute infection in hospitalized adults. The study found that the risk of acute kidney injury did not differ significantly between the two drugs, but patients treated with cefepime experienced more neurological dysfunction. These findings provide valuable insights into the comparative safety profiles of these antibiotics in the treatment of acute infection.

via JAMA Network|

#acute-infection #antibiotics #cefepime

medicine2 years ago•8 min saved

"Empirical Antibiotics for Sepsis Linked to Acute Kidney Injury"

A randomized clinical trial compared the use of piperacillin-tazobactam and cefepime for empirical treatment of sepsis and found no significant difference in the risk of acute kidney injury (AKI) between the two antibiotics. The trial also showed that patients treated with cefepime had fewer days alive and free of delirium and coma compared to those treated with piperacillin-tazobactam. The study provides evidence that piperacillin-tazobactam does not increase the risk of AKI compared to cefepime, but cefepime may be associated with a higher risk of neurological dysfunction.

via JAMA Network|

#acute-kidney-injury #antibiotics #cefepime