Tag

Camkii

All articles tagged with #camkii

neuroscience1 year ago

"Regulating CaMKII for Alzheimer's Mitigation"

Researchers at the University of Colorado have identified three types of drug inhibitors that can regulate the CaMKII protein, which plays a crucial role in brain and heart function, to potentially mitigate Alzheimer's and heart conditions. These inhibitors offer a valuable tool for scientists to study the protein's functions and could lead to significant progress in treating brain diseases without harmful side effects. The research provides accessible tools for scientists across various disciplines to explore the protein's roles and functions.

neuroscience2 years ago

"Unveiling the Link Between LTP Theory, Protein Rejuvenation, and Alzheimer's Prevention"

Researchers have challenged the long-held belief that enzymatic actions of the enzyme CaMKII are required for long-term potentiation (LTP), a key process in learning and memory. Instead, they discovered that LTP requires the structural functions of CaMKII. This breakthrough opens the possibility of developing a new class of CaMKII inhibitors that can protect against the effects of Alzheimer's disease without impairing memory and learning. The researchers are currently testing these inhibitors for their therapeutic potential in human Alzheimer's treatment.