A new hypothesis suggests that damage to the brainstem caused by viral infections like COVID-19 may underlie symptoms of Long COVID and ME/CFS, potentially explaining their multi-system effects and guiding future research and treatments.
A study using ultra-high-resolution 7T MRI scanners found that severe Covid-19 can cause lasting damage and inflammation in the brainstem, which may explain long-term physical and psychiatric symptoms such as fatigue, breathlessness, and anxiety, highlighting the importance of brain health in Covid-19 recovery.
Emily Balfour, a 25-year-old woman from London, is raising funds for a stem cell treatment that could prevent her brain from slipping down her spine and causing paralysis. Balfour suffered an ice skating injury at 14, which destabilized her spine, and was later diagnosed with Ehlers-Danlos syndrome. She now has a Chiari malformation and craniocervical instability, causing extreme pain, fatigue, paralysis, and loss of vision. The stem cell treatment, called a PICL, involves injecting stem cells into the spine through the back of the mouth, and Balfour hopes it will stabilize her skull and prevent further damage to her brainstem.