"Revitalizing Aging Brains: Promising Breakthroughs in Blood-based Rejuvenation"
Researchers from the University of California San Francisco (UCSF) and the University of Queensland have identified platelet factor 4 (PF4), a blood factor responsible for blood clot formation, as a key element in rejuvenating the aging brain. Injecting PF4 into aging mice reduced brain inflammation, improved brain cell connections, and enhanced memory and thinking abilities. The study also found that the longevity protein klotho and exercise can stimulate the release of PF4, further improving cognitive abilities in both young and old animals. This research opens up potential avenues for pharmacological interventions to counteract age-related cognitive decline.