
The Hidden Genetics Behind Asymptomatic COVID-19 Cases
A recent study published in Nature reveals that common genetic variation among individuals plays a role in mediating asymptomatic SARS-CoV-2 infection. The study focused on human leukocyte antigens (HLA), a group of genes that code for proteins used by the immune system to identify healthy cells and distinguish them from infected ones. Researchers found that individuals with the genetic variant HLA-B*15:01 were more likely to remain asymptomatic after infection. These individuals had immunological memory against a specific particle of SARS-CoV-2, possibly due to previous exposure to other coronaviruses. The findings provide insights into the immune response and may contribute to the development of better COVID-19 therapeutics and vaccines.

