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Asymptomatic Infection

All articles tagged with #asymptomatic infection

health2 years ago

The Hidden Genetics Behind Asymptomatic COVID-19 Cases

A recent study published in Nature reveals that common genetic variation among individuals plays a role in mediating asymptomatic SARS-CoV-2 infection. The study focused on human leukocyte antigens (HLA), a group of genes that code for proteins used by the immune system to identify healthy cells and distinguish them from infected ones. Researchers found that individuals with the genetic variant HLA-B*15:01 were more likely to remain asymptomatic after infection. These individuals had immunological memory against a specific particle of SARS-CoV-2, possibly due to previous exposure to other coronaviruses. The findings provide insights into the immune response and may contribute to the development of better COVID-19 therapeutics and vaccines.

health2 years ago

Unraveling the Mystery of Asymptomatic COVID-19: Researchers Discover Common Feature

A new study published in Nature suggests that "super dodgers," individuals who contract COVID-19 but never develop symptoms, may have a genetic advantage. These individuals are more than twice as likely to carry a specific gene variation that helps them destroy the SARS-CoV-2 virus. The mutation in the immune system-supporting human leukocyte antigen allows virus-killing cells, called T cells, to identify the coronavirus even if it is their first encounter. Understanding the biology behind asymptomatic infection has important implications for public health measures, vaccine design, and therapeutic development.

health2 years ago

Unraveling the Mystery of Asymptomatic COVID: Insights from Genetic Studies

A new study published in the scientific journal Nature suggests that people with a specific version of a gene known as HLA-B*15:01 are more likely to experience asymptomatic COVID-19 infections. Researchers recruited 30,000 individuals with European ancestry and found that those with the HLA-B*15:01 gene were over twice as likely to remain asymptomatic compared to those without the gene. If a person had two copies of the gene, they were 8½ times more likely to remain asymptomatic. The study also suggests that this gene may have provided some level of preexisting immunity to the pandemic coronavirus due to previous exposure to seasonal coronaviruses. Further research is needed to explore the impact of genetics on asymptomatic infections in people of non-European ancestries.