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Amines

All articles tagged with #amines

Revolutionary Chemistry Discovery Promises Major Advances in Medicine and Agriculture
science1 year ago

Revolutionary Chemistry Discovery Promises Major Advances in Medicine and Agriculture

Scientists at the Technion have developed triazenolysis, a novel chemical process that converts alkenes into multifunctional amines, offering significant advancements in polymer, pharmaceutical, and agricultural production. Unlike the traditional ozonolysis, which forms carbon-oxygen bonds, triazenolysis efficiently creates carbon-nitrogen bonds, enhancing its applicability across various fields. This breakthrough, detailed in Nature Chemistry, was achieved by a team led by Prof. Mark Gandelman and supported by the Israel Science Foundation.

science2 years ago

Cu-catalyzed N-alkylation of aliphatic amines with enantioconvergence.

Researchers have developed a new method for the enantioselective N-alkylation of aliphatic amines with α-carbonyl alkyl chlorides using chiral tridentate anionic ligands and copper catalysts. The method can convert feedstock chemicals, including ammonia and pharmaceutically-relevant amines, into unnatural chiral α-amino amides under mild and robust conditions with excellent enantioselectivity and functional group tolerance. The method has potential applications in the expedited synthesis of diverse amine drug molecules.