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Amines

All articles tagged with #amines

Revolutionary Chemistry Discovery Promises Major Advances in Medicine and Agriculture

Originally Published 1 year ago — by SciTechDaily

Scientists at the Technion have developed triazenolysis, a novel chemical process that converts alkenes into multifunctional amines, offering significant advancements in polymer, pharmaceutical, and agricultural production. Unlike the traditional ozonolysis, which forms carbon-oxygen bonds, triazenolysis efficiently creates carbon-nitrogen bonds, enhancing its applicability across various fields. This breakthrough, detailed in Nature Chemistry, was achieved by a team led by Prof. Mark Gandelman and supported by the Israel Science Foundation.

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Cu-catalyzed N-alkylation of aliphatic amines with enantioconvergence.

Originally Published 2 years ago — by Nature.com

Researchers have developed a new method for the enantioselective N-alkylation of aliphatic amines with α-carbonyl alkyl chlorides using chiral tridentate anionic ligands and copper catalysts. The method can convert feedstock chemicals, including ammonia and pharmaceutically-relevant amines, into unnatural chiral α-amino amides under mild and robust conditions with excellent enantioselectivity and functional group tolerance. The method has potential applications in the expedited synthesis of diverse amine drug molecules.

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