All articles tagged with #am404
Originally Published 6 months ago — by Live Science
A new study suggests that Tylenol's active byproduct, AM404, may block pain signals at the nerve level by inhibiting sodium channels, challenging previous beliefs about its mechanism and opening avenues for safer painkillers, though further research in humans is needed.
Originally Published 7 months ago — by Neuroscience News
A study from Hebrew University reveals that paracetamol (acetaminophen) not only acts in the brain but also produces AM404 in peripheral nerves, which blocks sodium channels responsible for transmitting pain, offering a new understanding of its pain-relief mechanism and potential for targeted, side-effect-free treatments.
Originally Published 7 months ago — by Medical Xpress
A new study reveals that acetaminophen (Tylenol) not only works in the brain but also directly affects pain-sensing nerves outside the brain by producing AM404, which blocks pain signals, potentially leading to safer and more effective painkillers.