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Adverse Side Effects

All articles tagged with #adverse side effects

"Pfizer's Weight-Loss Pill: Another Flop in the Obesity Drug Market"

Originally Published 2 years ago — by CNBC

Pfizer has announced that it will stop developing its twice-daily weight loss pill, danuglipron, after obese patients experienced high rates of adverse side effects in a midstage clinical trial. This comes after Pfizer scrapped a different once-daily pill earlier this year due to elevated liver enzymes. The difficulties in developing effective and safe weight loss treatments are highlighted by the long list of obesity drugs that have been discontinued or pulled from the market due to unintended consequences, such as cancer risks, cardiovascular risks, and serious psychiatric problems. Despite recent breakthrough medications, including Novo Nordisk's Wegovy and Eli Lilly's Mounjaro, the path to treating obesity remains challenging.

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Pfizer's Weight Loss Pill Plans Derailed by Adverse Effects and Rival Competition

Originally Published 2 years ago — by CNBC

Pfizer has announced that it will discontinue the development of the twice-daily version of its experimental weight loss pill due to high rates of adverse side effects observed in a mid-stage clinical study. The drug showed promising results in terms of weight loss, but patients had difficulty tolerating the medication, with gastrointestinal issues being the most common side effect. Pfizer still plans to release phase two trial data on a once-a-day version of the drug in 2024, which will determine whether it will proceed to phase three studies. This setback puts Pfizer further behind competitors in the weight loss drug market, such as Eli Lilly and Novo Nordisk.

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