Tag

Acute Mi

All articles tagged with #acute mi

health1 year ago•7 min saved

"Rethinking Beta-Blockers After Heart Attack: Insights from REDUCE-AMI Trial"

The REDUCE-AMI study presented at the American College of Cardiology (ACC) 2024 Scientific Session suggests that beta-blockers do not reduce the risk of death or recurrent MI in patients with acute MI and preserved ejection fraction, challenging their long-standing use in post-MI care. The study, published in the New England Journal of Medicine, found no benefit of beta-blockers in reducing the primary endpoint of death or recurrent MI over a median follow-up of 3.5 years. While the study has limitations, it may prompt a reevaluation of the reflexive prescription of beta-blockers after acute MI, potentially leading to changes in clinical practice.

via TCTMD|

#acute-mi #beta-blockers #cardiology

medical-research2 years ago•8 min saved

Dapagliflozin Triumphs in Cardiometabolic Outcomes Post Acute MI

The DAPA-MI trial, which investigated the use of dapagliflozin in acute myocardial infarction (MI) patients, showed significant improvements in cardiometabolic outcomes but did not have an impact on cardiovascular death or heart failure hospitalizations, the trial's original primary endpoint. The trial had to switch to a hierarchical win-ratio analysis due to low event rates, combining several clinical endpoints. The results suggest that dapagliflozin may have benefits in reducing the risk of developing heart failure, diabetes, hypertension, and other cardiometabolic conditions in acute MI patients. However, some experts remain skeptical about the implementation of dapagliflozin in this patient population, citing the modest absolute reductions in new diabetes diagnoses and weight loss.

via TCTMD|

#acute-mi #cardiometabolic-outcomes #dapa-mi-trial