Mitochondrial Free Radicals in Brain Cells Linked to Dementia Progression
TL;DR Summary
Scientists at Weill Cornell Medicine discovered that free radicals produced in astrocytes' mitochondria contribute to dementia, and blocking these radicals with targeted compounds reduced inflammation and protected neurons in animal models, opening new avenues for treatment.
- Scientists find hidden brain source that fuels dementia ScienceDaily
- Mitochondrial complex III-derived ROS amplify immunometabolic changes in astrocytes and promote dementia pathology Nature
- Study pinpoints source of free radicals in the brain that may fuel dementia Medical Xpress
- Mitochondrial ROS Boost Astrocyte Changes, Drive Dementia Bioengineer.org
- Blocking brain cell free radicals may help prevent dementia: Study Anadolu Ajansı
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