Key Mutation in H5N1 May Increase Human Transmission Risk

A NIH-funded study published in Science reveals that a single mutation in the hemagglutinin protein of the H5N1 avian influenza virus could potentially enhance its ability to infect humans by allowing it to bind to human-type cell receptors. While current strains are not easily transmissible among humans, the findings highlight the importance of ongoing surveillance and monitoring for genetic changes in the virus to prevent potential outbreaks. The research underscores the need for continued public health preparedness and outbreak control efforts.