"Visualizing Protein Collapse: Unveiling the Critical Moments in Alzheimer's and Other Diseases"

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Source: ScienceAlert
"Visualizing Protein Collapse: Unveiling the Critical Moments in Alzheimer's and Other Diseases"
Photo: ScienceAlert
TL;DR Summary

Researchers have developed a new imaging technique to capture the moment when proteins associated with neurodegenerative diseases like Alzheimer's and ALS begin to aggregate. By closely monitoring the transition of proteins from their liquid to solid phase, the team observed the formation of dense protein condensates that eventually solidified into clumps. This breakthrough provides insights into the physical process underlying neurodegenerative diseases and could lead to a better understanding of protein interactions.

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