Unveiling the Atomic Structure of Synthetic DNA

Researchers have used X-ray crystallography to observe synthetic DNA, known as DNAzymes, at an atomic level, providing insights into its structure and potential applications in medical diagnosis and treatment. This breakthrough could lead to the development of more effective treatments for diseases like cancer and retinal degeneration. The study, funded by a Ralph E. Powe Junior Faculty Enhancement Award, sheds light on the catalytic properties of synthetic DNA and opens up possibilities for enhancing its scissor-like activity. By understanding how to optimize the technology, it could be applied as a therapeutic solution for various diseases.