"Revolutionary Bioactive Clusters: 3D Imaging and Inhibition of Acute Inflammation"

Researchers have developed bioactive gold-copper clusters with strong near-infrared II (NIR-II) fluorescence and potent enzyme-mimicking activities. These clusters can be used for highly accurate monitoring of cisplatin-induced kidney injury and inhibition of oxidative stress and inflammation in multiple organs, particularly in the kidneys and brain. The clusters showed excellent photostability and can be cleared through the kidneys, allowing for real-time imaging and early intervention in acute kidney injury. This research has promising implications for the diagnosis and treatment of oxidative stress-related diseases.