"microbeMASST: Advancing Microbial Metabolomics with Taxonomic Insight and Mass Spectrometry"

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Source: Nature.com
"microbeMASST: Advancing Microbial Metabolomics with Taxonomic Insight and Mass Spectrometry"
Photo: Nature.com
TL;DR Summary

microbeMASST is a new search tool that leverages public mass spectrometry repository data to identify the microbial origin of known and unknown metabolites and map them to their microbial producers. It contains a reference database of microbial monocultures and allows users to search tandem mass spectrometry (MS/MS) spectra obtained from their experiments against the repository. The tool provides search results within seconds and displays them in interactive taxonomic trees, enabling users to filter results and access additional information. It has been used to identify microbial metabolites in mouse datasets and has the potential to enhance understanding of microbial metabolites across various ecosystems.

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