Universal Access to Lifesaving Drug: A Step Closer to Reality

A study conducted by the London School of Hygiene & Tropical Medicine (LSHTM) has shown that tranexamic acid (TXA), a drug used to treat severe postpartum bleeding, can be safely administered intramuscularly and orally. The intramuscular route reaches therapeutic levels quickly and is well-tolerated, making it a potential alternative to intravenous administration, particularly in low and middle-income countries where healthcare facilities may be limited. Oral TXA is also well-tolerated but takes longer to reach therapeutic blood concentrations, making it less suitable for emergency treatment. Severe postpartum bleeding is a leading cause of maternal death globally, and these findings could pave the way for more accessible and effective treatment options. Comparative Phase 3 clinical trials are set to begin in August to further evaluate the effectiveness of intramuscular administration in reducing postpartum bleeding.