The Role of Y Chromosome Loss in Cancer Growth and Aggressiveness.
TL;DR Summary
Loss of the Y chromosome in cancer cells allows them to evade the body's adaptive immune response, leading to increased cancer growth. This finding could explain why men are more susceptible to certain types of cancer. The study also suggests that targeting the Y chromosome could be a potential strategy for improving immunotherapy treatments for bladder cancer.
Topics:science#adaptive-immunity#bladder-cancer#cancer-growth#cancer-research#immunotherapy#y-chromosome
- Y chromosome loss in cancer drives growth by evasion of adaptive immunity Nature.com
- Study: Genetics can explain why sex matters in some cancer outcomes. USA TODAY
- How the Y chromosome makes some cancers more deadly for men Nature.com
- Why bladder cancer cells that shed their Y chromosome become more aggressive Nature.com
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