"Bioengineered Embryo and Neural Tissue Models Advance Medical Research"

Scientists have established a model of the human post-implantation embryo, called a human embryoid, using pluripotent stem cells. The embryoid is comprised of embryonic and extraembryonic tissues and contains a pluripotent epiblast-like domain surrounded by extraembryonic-like tissues. The model will allow scientists to probe key questions of human post-implantation development, a critical window when significant numbers of pregnancies fail, and study tissue-tissue crosstalk during these stages.