"Uncovering the Genetic Links to Left-Handedness: Insights from Rare Variants"

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Source: ZME Science
"Uncovering the Genetic Links to Left-Handedness: Insights from Rare Variants"
Photo: ZME Science
TL;DR Summary

Researchers at the Max Planck Institute have identified rare protein-altering genetic variants associated with left-handedness, shedding light on the inheritable nature of this trait. Using data from the UK Biobank, they found that microtubule-related genes, such as TUBB4B, may play a role in setting up brain asymmetries. Additionally, genes associated with autism, DSCAM and FOXP1, were linked to left-handedness, providing potential insights into conditions like autism and schizophrenia. The study highlights the complexity of handedness as a polygenic trait and paves the way for further exploration of brain asymmetry in embryonic development.

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