The Influence of Ancient Viruses on Brain Evolution

A study published in Cell reveals that ancient retroviruses are responsible for the development of myelin, a crucial component of complex vertebrate brains. The discovery of "RetroMyelin," a gene sequence derived from ancient retroviruses, highlights the impact of viral genes on vertebrate evolution. Experimental disruption of RetroMyelin in zebrafish and frogs led to significantly reduced myelin production, demonstrating its functional role in myelination across mammals, amphibians, and fish. This research challenges previous understandings of evolutionary biology and opens new avenues for exploring the intricate relationship between viruses and vertebrate development.