Astrocyte CCN1 Enhances Stability of Adult Neural Circuits
TL;DR Summary
The study identifies astrocyte-secreted CCN1 as a key factor in maintaining neural circuit stability in the adult brain, particularly in the visual cortex, by regulating synaptic maturation, inhibitory neuron development, and oligodendrocyte maturation, thereby restricting plasticity and preserving functional connectivity.
- Astrocyte CCN1 stabilizes neural circuits in the adult brain Nature
- How do brains stay stable, and when might a dose of flexibility be helpful? Medical Xpress
- Astrocyte CCN1 Fortifies Adult Brain Circuits Bioengineer.org
- Astrocyte-Derived CCN1 Identified as Key to Stability of Binocular Neural Circuits in Adult Visual Cortex geneonline.com
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