Innovative Methods Unveil Cancer Evolution and Resistance in Ovarian Cancer

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Source: Nature
Innovative Methods Unveil Cancer Evolution and Resistance in Ovarian Cancer
Photo: Nature
TL;DR Summary

The study introduces CloneSeq-SV, a method combining single-cell whole-genome sequencing and circulating tumor DNA analysis to track clonal evolution and structural variants in ovarian cancer, revealing mechanisms of drug resistance and potential for adaptive therapy.

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