Unraveling the Mystery of King George III's Illness.

King George III's periodic bouts of serious illness and erratic behavior have led to various retrospective diagnoses, including acute porphyria and severe mental illness. While the porphyria theory was popularized in the mid-1960s, recent research suggests that George's madness may have been a version of severe mental illness. A 2005 hair analysis found high amounts of arsenic, which could have contributed to his poor mental health. However, diagnosing a king who died 200 years ago without physical evidence remains a challenge.