"New Gene Mutation and Activity Changes Linked to ALS Uncovered"

Researchers from Harvard University have identified gene activity changes in motor nerve cells that may explain their selective degeneration in amyotrophic lateral sclerosis (ALS). The study, funded by the NIH and published in Nature Aging, found that ALS-associated genes show elevated activity in Betz cells, leading to protein disruptions and neurodegeneration. These findings offer new insights into ALS and potential therapeutic targets, emphasizing the need for future studies with larger patient samples.