Revealing the Surprising Truth Behind Cancer Drug Failures

A study from the University of Wisconsin–Madison reveals that common chemotherapy drugs, known as microtubule poisons, do not work by halting cell division as previously believed. Instead, these drugs alter mitosis, causing abnormal division that can lead to the death of cancer cells. The findings have significant implications for drug discovery efforts, as researchers have been focusing on developing therapies that mimic the supposed mechanism of microtubule poisons. The study suggests that efforts should be redirected towards disrupting mitosis and chromosomal segregation to improve cancer treatments.