Parabrachial Nucleus: The Brain's Key to Turning Off Chronic Pain
TL;DR Summary
Research reveals a brainstem circuit involving Y1 receptor neurons that can suppress long-term pain by prioritizing survival needs like hunger and fear, opening new avenues for pain treatment targeting brain mechanisms rather than injury sites.
- Hunger, Fear, and the Brain’s Hidden Switch to Turn Off Chronic Pain Neuroscience News
- A built-in ‘off switch’ to stop persistent pain Penn Today
- A parabrachial hub for need-state control of enduring pain Nature
- Parabrachial Nucleus Identified as Key Brainstem Hub in Chronic Pain Processing geneonline.com
- Parabrachial Hub Governs Persistent Pain States Bioengineer.org
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