"Promising Drug Candidates for Targeting HIV-Infected Cells"

Researchers have identified new drug candidates that could help the immune system detect HIV-infected cells by targeting the protein Nef, which allows the cells to evade detection. These drug candidates, called PROTACs, could potentially unmask the reservoir of dormant HIV-infected cells that current antiretroviral therapy cannot clear. While the discovery has generated excitement, further research and preclinical testing in animal models are needed before potential clinical trials can be pursued.