"Comparing Natural vs. Synthetic Psilocybin: Unveiling Enhanced Therapeutic Effects"

A new study suggests that full-spectrum psychedelic mushroom extract produces more potent and prolonged effects on synaptic plasticity compared to chemically synthesized psilocybin alone, indicating a potential entourage effect similar to cannabis. The findings have implications for psychedelic-assisted therapy and highlight the therapeutic potential of natural psychedelic compounds. The study, conducted on mice, found that the mushroom extract increased synaptic proteins in the brain more than psilocybin alone, suggesting a quantitatively stronger therapeutic mechanism. Further research is needed to identify the specific molecules responsible for these enhanced effects. This study parallels growing research on the entourage effect in cannabis, indicating that a better understanding of the relationships between various chemical components is crucial for unraveling the complete therapeutic potential of both psychedelic mushrooms and marijuana.