Maternal Stress During Pregnancy Linked to Childhood Eczema Development
TL;DR Summary
Maternal prenatal stress triggers early-life eczema in offspring by programming fetal mast cells through elevated corticosterone levels, leading to skin barrier alterations and heightened mechanical sensitivity, with effects reversible by corticosterone normalization.
Topics:health#eczema#fetal-mast-cells#glucocorticoids#health-and-medicine#maternal-stress#neuroimmune-interactions
- Maternal stress triggers early-life eczema through fetal mast cell programming Nature
- The foundations of eczema may start to be laid down in the womb New Scientist
- Study in mice reveals a link between maternal stress during pregnancy and childhood eczema Medical Xpress
- Stress in mothers causes eczema in newborn mice through immune cell changes News-Medical
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