Dual-ROS Iron MOF Nanotherapy Eradicates Tumors in Mice

OSU researchers developed an iron-based metal-organic framework nanomaterial that, inside tumor cells, catalyzes both hydroxyl radical and singlet oxygen production, delivering a dual ROS attack that eradicated breast cancer tumors in mice with no systemic toxicity and sparing healthy tissue; this chemodynamic therapy approach is being tested on other cancers before advancing to human trials.